ACTIVATED NETWORKING OF PLATELET ACTIVATING FACTOR RECEPTOR AND FAK/STAT1 INDUCES MALIGNANT POTENTIAL IN BRCA1-MUTANT AT-RISK OVARIAN EPITHELIUM

Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epithelium

Abstract Objectives It is essential to understand the molecular basis of ovarian cancer etiology and tumor development to provide more effective preventive and therapeutic approaches to reduce mortality.Particularly, the molecular targets and pathways involved in early malignant transformation are still not clear.Pro-inflammatory lipids and pathway

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Developing a Bayesian network model for understanding river catchment resilience under future change scenarios

The resilience of river catchments and the vital socio-ecological services they provide are threatened by the cumulative impacts of future climatic and socio-economic change.Stakeholders who manage freshwaters require tools for increasing their understanding of catchment system resilience when making strategic decisions.However, unravelling causes,

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